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Severe, persistent, and fatal T‐cell immunodeficiency following therapy for infantile leukemia

We describe five cases of children who completed chemotherapy for infantile acute lymphoblastic leukemia (ALL) and soon after were diagnosed with severe T‐cell, non‐HIV immunodeficiency, with varying B‐cell and NK‐cell depletion. There was near absence of CD3(+), CD4(+), and CD8(+) cells. All patien...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Geerlinks, Ashley V., Issekutz, Thomas, Wahlstrom, Justin T., Sullivan, Kathleen E., Cowan, Morton J., Dvorak, Christopher C., Fernandez, Conrad V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168093/
https://ncbi.nlm.nih.gov/pubmed/27354010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.26108
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