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CXCR4 Antagonists as Stem Cell Mobilizers and Therapy Sensitizers for Acute Myeloid Leukemia and Glioblastoma?

Glioblastoma is the most aggressive and malignant primary brain tumor in adults and has a poor patient survival of only 20 months after diagnosis. This poor patient survival is at least partly caused by glioblastoma stem cells (GSCs), which are slowly-dividing and therefore therapy-resistant. GSCs a...

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Détails bibliographiques
Publié dans:Biology (Basel)
Auteurs principaux: Hira, Vashendriya V.V., Van Noorden, Cornelis J.F., Molenaar, Remco J.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168055/
https://ncbi.nlm.nih.gov/pubmed/32079173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology9020031
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