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MicroRNA-584 Impairs Cellular Proliferation and Sensitizes Osteosarcoma Cells to Cisplatin and Taxanes by Targeting CCN2

BACKGROUND: Osteosarcoma (OS), an aggressive malignant neoplasm, exhibits osteoblastic differentiation. Cisplatin (DDP) and taxanes are among the most effective drugs for OS patients. Nevertheless, the drug resistance remains a main limitation to efficacious chemotherapy in OS. The current report se...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Li, Li, Kong, Xiang’an, Zang, Mousheng, Hu, Bin, Fang, Xing, Gui, Binjie, Hu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167371/
https://ncbi.nlm.nih.gov/pubmed/32346311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S246545
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