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The role of mouse models in colorectal cancer research—The need and the importance of the orthotopic models

Colorectal cancer is a worldwide health burden, with high incidence and mortality, especially in the advanced stages of the disease. Preclinical models are very important and valuable to discover and validate early and specific biomarkers as well as new therapeutic targets. In order to accomplish th...

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Detalles Bibliográficos
Publicado en:Animal Model Exp Med
Main Authors: Oliveira, Rui C., Abrantes, Ana Margarida, Tralhão, José Guilherme, Botelho, Maria Filomena
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167241/
https://ncbi.nlm.nih.gov/pubmed/32318654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ame2.12102
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