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Inactivation of 12 viruses by heating steps applied during manufacture of a hepatitis B vaccine

The efficacy of two heating cycles (90 sec at 103°C and 10 hr at 65°C) used during manufacture of a plasma‐derived hepatitis‐B vaccine was validated for the inactivation of 12 virus families. A period of 15 min warming up to 65°C had already completely inactivated representatives of nine virus famil...

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Detalhes bibliográficos
Publicado no:J Med Virol
Main Authors: Lelie, P. N., Reesink, H. W., Lucas, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7166500/
https://ncbi.nlm.nih.gov/pubmed/2828525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.1890230313
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