Recurrent mutations associated with isolation and passage of SARS coronavirus in cells from non‐human primates

Four clinical isolates of SARS coronavirus were serially passaged in two primate cell lines (FRhK4 and Vero E6). Viral genetic sequences encoding for structural proteins and open reading frames 6–8 were determined in the original clinical specimen, the initial virus isolate (passage 0) and at passag...

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Bibliographic Details
Published in:J Med Virol
Main Authors: Poon, Leo L.M., Leung, Cynthia S.W., Chan, Kwok H., Yuen, Kwok Y., Guan, Yi, Peiris, Joseph S.M.
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7166449/
https://ncbi.nlm.nih.gov/pubmed/15977248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.20379
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