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Biosynthesis of Amino Acid-Derived α-Pyrones by an NRPS-NRPKS Hybrid Megasynthetase in Fungi ()
A nonribosomal peptide synthetase (NRPS)-nonreducing polyketide synthase (NRPKS) hybrid enzyme (AnATPKS) from Aspergillus niger was shown to produce amino acid derived α-pyrone natural products (pyrophen and campyrone B). Biochemical characterization of the NRPS module in vitro reveals that the aden...
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| Udgivet i: | J Nat Prod |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7166049/ https://ncbi.nlm.nih.gov/pubmed/32159958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.9b00989 |
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