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Emerging roles of deubiquitinases in cancer‐associated pathways

Deubiquitinases (DUBs) are emerging as important regulators of many pathways germane to cancer. They may regulate the stability of key oncogenes, exemplified by USP28 stabilisation of c‐Myc. Alternatively they can negatively regulate ubiquitin‐dependent signalling cascades such as the NF‐κB activati...

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Podrobná bibliografie
Vydáno v:IUBMB Life
Hlavní autoři: Sacco, Joseph J., Coulson, Judy M., Clague, Michael J., Urbé, Sylvie
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., a Wiley company 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165618/
https://ncbi.nlm.nih.gov/pubmed/20073038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.300
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