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Inhibition of BRD4 prevents proliferation and epithelial–mesenchymal transition in renal cell carcinoma via NLRP3 inflammasome-induced pyroptosis

BRD4 has long been implicated in many different pathological processes, in particular, the development of cancer and inflammation. Pyroptosis is a newly recognized type of inflammatory programmed cell death. However, the correlation between BRD4 and pyroptosis in renal cell carcinoma (RCC) remains e...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Tan, Yi-Fan, Wang, Min, Chen, Zhi-Yuan, Wang, Lei, Liu, Xiu-Heng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165180/
https://ncbi.nlm.nih.gov/pubmed/32303673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2431-2
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