Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia–reperfusion injury

Pyroptosis, a proinflammatory form of programmed cell death, plays important roles in the pathogenesis of many diseases. Inflammasome activation, which has been shown in hepatic ischemia–reperfusion injury (IRI), is demonstrated to be closely associated with pyroptosis, indicating that pyroptosis ma...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Jichang, Zhao, Jie, Xu, Min, Li, Meng, Wang, Bingrui, Qu, Xiaoye, Yu, Chang, Hang, Hualian, Xia, Qiang, Wu, Hailong, Sun, Xuehua, Gu, Jinyang, Kong, Xiaoni
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165177/
https://ncbi.nlm.nih.gov/pubmed/32303674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2437-9
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