Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia–reperfusion injury

Pyroptosis, a proinflammatory form of programmed cell death, plays important roles in the pathogenesis of many diseases. Inflammasome activation, which has been shown in hepatic ischemia–reperfusion injury (IRI), is demonstrated to be closely associated with pyroptosis, indicating that pyroptosis ma...

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Pubblicato in:Cell Death Dis
Autori principali: Li, Jichang, Zhao, Jie, Xu, Min, Li, Meng, Wang, Bingrui, Qu, Xiaoye, Yu, Chang, Hang, Hualian, Xia, Qiang, Wu, Hailong, Sun, Xuehua, Gu, Jinyang, Kong, Xiaoni
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165177/
https://ncbi.nlm.nih.gov/pubmed/32303674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2437-9
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