Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2‐polarizing conditions

Background Human thymic stromal lymphopoietin (TSLP) is expressed in the human asthmatic lung and activates dendritic cells (DCs) to strongly induce proallergic T‐helper type 2 (Th2) cell responses, suggesting that TSLP plays a critical role in the pathophysiology of human asthma. Th2 cells are pred...

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Detalhes bibliográficos
Publicado no:Clin Exp Allergy
Main Authors: Tanaka, J., Watanabe, N., Kido, M., Saga, K., Akamatsu, T., Nishio, A., Chiba, T.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Original Articles: Editor's Choice: Basic Mechanisms in Allergic Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164823/
https://ncbi.nlm.nih.gov/pubmed/19055649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2008.03151.x
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