Plasma membrane expression of G protein-coupled estrogen receptor (GPER)/G protein-coupled receptor 30 (GPR30) is associated with worse outcome in metachronous contralateral breast cancer

BACKGROUND: G protein-coupled estrogen receptor (GPER), or G protein-coupled receptor 30 (GPR30), is reported to mediate non-genomic estrogen signaling. GPR30 associates with breast cancer (BC) outcome and may contribute to tamoxifen resistance. We investigated the expression and prognostic signific...

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Veröffentlicht in:PLoS One
Hauptverfasser: Tutzauer, Julia, Sjöström, Martin, Bendahl, Pär-Ola, Rydén, Lisa, Fernö, Mårten, Leeb-Lundberg, L. M. Fredrik, Alkner, Sara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164601/
https://ncbi.nlm.nih.gov/pubmed/32302351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231786
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