Physicochemical and biological evaluation of JR-131 as a biosimilar to a long-acting erythropoiesis-stimulating agent darbepoetin alfa

Renal anemia is predominantly caused by a relative deficiency in erythropoietin (EPO). Conventional treatment for renal anemia includes the use of recombinant human EPO (rhEPO) or a long-acting erythropoiesis-activating agent named darbepoetin alfa, which is a modified rhEPO with a carbohydrate chai...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Tani, Junya, Ito, Yae, Tatemichi, Satoshi, Yamakami, Makoto, Fukui, Tsuyoshi, Hatano, Yukichi, Kakimoto, Shinji, Kotani, Ayaka, Sugimura, Atsushi, Mihara, Kazutoshi, Yamamoto, Ryuji, Tanaka, Noboru, Minami, Kohtaro, Takahashi, Kenichi, Hirato, Tohru
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164597/
https://ncbi.nlm.nih.gov/pubmed/32302352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231830
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