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Mechanopharmacology and Synergistic Relaxation of Airway Smooth Muscle

Asthmatic airways are stiffer than normal. We have shown that the cytoskeletal passive stiffness of airway smooth muscle (ASM) can be regulated by intracellular signaling pathways, especially those associated with Rho kinase (ROCK). We have also shown that an oscillatory strain reduces the passive s...

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Bibliografski detalji
Izdano u:J Eng Sci Med Diagn Ther
Glavni autori: Wang, Lu, Chitano, Pasquale, Paré, Peter D., Seow, Chun Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Mechanical Engineers 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164492/
https://ncbi.nlm.nih.gov/pubmed/32328573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1115/1.4042477
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