Enhanced NETosis generation in radiographic axial spondyloarthritis: utility as biomarker for disease activity and anti-TNF-α therapy effectiveness

BACKGROUND: Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory form of arthritis in which tumor necrosis factor (TNF)-α, a potent inducer of inflammatory response and a key regulator of innate immunity and of Th1 immune responses, plays a central role. NETosis is a mechanism of...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Ruiz-Limon, Patricia, Ladehesa-Pineda, Maria Lourdes, Castro-Villegas, Maria del Carmen, Abalos-Aguilera, Maria del Carmen, Lopez-Medina, Clementina, Lopez-Pedrera, Chary, Barbarroja, Nuria, Espejo-Peralbo, Daniel, Gonzalez-Reyes, Jose Antonio, Villalba, Jose Manuel, Perez-Sanchez, Carlos, Escudero-Contreras, Alejandro, Collantes-Estevez, Eduardo, Font-Ugalde, Pilar, Jimenez-Gomez, Yolanda
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164280/
https://ncbi.nlm.nih.gov/pubmed/32303225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00634-1
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