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Structural characterization of a fusion glycoprotein from a retrovirus that undergoes a hybrid 2‐step entry mechanism

Entry of enveloped viruses into host cells is mediated by their surface envelope glycoproteins (Env). On the surface of the virus, Env is in a metastable, prefusion state, primed to catalyze the fusion of the viral and host membranes. An external trigger is needed to promote the drastic conformation...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Aydin, Halil, Smrke, Brianna M., Lee, Jeffrey E.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164122/
https://ncbi.nlm.nih.gov/pubmed/24036886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-232371
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