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Activity‐based probes for the ubiquitin conjugation–deconjugation machinery: new chemistries, new tools, and new insights

The reversible post‐translational modification of proteins by ubiquitin and ubiquitin‐like proteins regulates almost all cellular processes, by affecting protein degradation, localization, and complex formation. Deubiquitinases (DUBs) are proteases that remove ubiquitin modifications or cleave ubiqu...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Hewings, David S., Flygare, John A., Bogyo, Matthew, Wertz, Ingrid E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163952/
https://ncbi.nlm.nih.gov/pubmed/28196299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14039
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