Leadzyme formed in vivo interferes with tobacco mosaic virus infection in Nicotiana tabacum

We developed a new method for inhibiting tobacco mosaic virus infection in tobacco plants based on specific RNA hydrolysis induced by a leadzyme. We identified a leadzyme substrate target sequence in genomic tobacco mosaic virus RNA and designed a 16‐mer oligoribonucleotide capable of forming a spec...

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Publicat a:FEBS J
Autors principals: Wyszko, Eliza, Nowak, Monika, Pospieszny, Henryk, Szymanski, Maciej, Pas, Jakub, Barciszewska, Mirosława Z., Barciszewski, Jan
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2006
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163940/
https://ncbi.nlm.nih.gov/pubmed/17032353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2006.05497.x
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