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Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV-2

Peptide inhibitors against the SARS-CoV-2 coronavirus, currently causing a worldwide pandemic, are designed and simulated. The inhibitors are mostly formed by two sequential self-supporting α-helices (bundle) extracted from the protease domain (PD) of angiotensin-converting enzyme 2 (ACE2), which bi...

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Detaylı Bibliyografya
Yayımlandı:ACS Nano
Asıl Yazarlar: Han, Yanxiao, Král, Petr
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163933/
https://ncbi.nlm.nih.gov/pubmed/32286790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.0c02857
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