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Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV-2
Peptide inhibitors against the SARS-CoV-2 coronavirus, currently causing a worldwide pandemic, are designed and simulated. The inhibitors are mostly formed by two sequential self-supporting α-helices (bundle) extracted from the protease domain (PD) of angiotensin-converting enzyme 2 (ACE2), which bi...
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| Pubblicato in: | ACS Nano |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7163933/ https://ncbi.nlm.nih.gov/pubmed/32286790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.0c02857 |
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