Up‐regulation of indoleamine 2,3‐dioxygenase 1 (IDO1) expression and catalytic activity is associated with immunosuppression and poor prognosis in penile squamous cell carcinoma patients

BACKGROUND: Indoleamine 2,3‐dioxygenase 1 (IDO1) and tryptophan (Trp) catabolism have been demonstrated to play an important role in tumor immunosuppression. This study examined the expression and catalytic activity of IDO1 in penile squamous cell carcinoma (PSCC) and explored their clinical signifi...

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Detalhes bibliográficos
Publicado no:Cancer Commun (Lond)
Main Authors: Zhou, Qiang‐hua, Han, Hui, Lu, Jia‐bin, Liu, Ting‐yu, Huang, Kang‐bo, Deng, Chuang‐zhong, Li, Zai‐shang, Chen, Jie‐ping, Yao, Kai, Qin, Zi‐ke, Liu, Zhuo‐wei, Li, Yong‐hong, Guo, Sheng‐jie, Ye, Yun‐lin, Zhou, Fang‐jian, Liu, Ran‐yi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163927/
https://ncbi.nlm.nih.gov/pubmed/32125093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cac2.12001
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