Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1‐integrin

Although CD8 T cells are key players in neuroinflammation, little is known about their trafficking cues into the central nervous system (CNS). We used a murine model of CNS autoimmunity to define the molecules involved in cytotoxic CD8 T‐cell migration into the CNS. Using a panel of mAbs, we here sh...

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Bibliografske podrobnosti
izdano v:Eur J Immunol
Main Authors: Martin‐Blondel, Guillaume, Pignolet, Béatrice, Tietz, Silvia, Yshii, Lidia, Gebauer, Christina, Perinat, Therese, Van Weddingen, Isabelle, Blatti, Claudia, Engelhardt, Britta, Liblau, Roland
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Cellular Immune Response
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163664/
https://ncbi.nlm.nih.gov/pubmed/26358409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545632
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