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Primary and secondary hemophagocytic lymphohistiocytosis have different patterns of T‐cell activation, differentiation and repertoire

Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening inflammatory syndrome characterized by hyperactivation of lymphocytes and histiocytes. T cells play a key role in HLH pathogenesis, but their differentiation pattern is not well characterized in patients with active HLH. We compared T‐ce...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Ammann, Sandra, Lehmberg, Kai, zur Stadt, Udo, Janka, Gritta, Rensing‐Ehl, Anne, Klemann, Christian, Heeg, Maximilian, Bode, Sebastian, Fuchs, Ilka, Ehl, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163530/
https://ncbi.nlm.nih.gov/pubmed/27925643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646686
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