Systemic Expression of a Viral RdRP Protects against Retrovirus Infection and Disease

The innate immune system is normally programmed for immediate but transient upregulation in response to invading pathogens, and interferon (IFN)-stimulated gene (ISG) activation is a central feature. In contrast, chronic innate immune system activation is typically associated with autoimmunity and a...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Miller, Caitlin M., Barrett, Bradley S., Chen, Jianfang, Morrison, James H., Radomile, Caleb, Santiago, Mario L., Poeschla, Eric M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2020
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163129/
https://ncbi.nlm.nih.gov/pubmed/32051266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00071-20
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