The Elusive Link Between Cancer FDG Uptake and Glycolytic Flux Explains the Preserved Diagnostic Accuracy of PET/CT in Diabetes

This study aims to verify in experimental models of hyperglycemia induced by streptozotocin (STZ-DM) to what degree the high competition between unlabeled glucose and metformin (MET) treatment might affect the accuracy of cancer FDG imaging. The study included 36 “control” and 36 “STZ-DM” Balb/c mic...

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Vydáno v:Transl Oncol
Hlavní autoři: Cossu, Vanessa, Bauckneht, Matteo, Bruno, Silvia, Orengo, Anna Maria, Emionite, Laura, Balza, Enrica, Castellani, Patrizia, Piccioli, Patrizia, Miceli, Alberto, Raffa, Stefano, Borra, Anna, Donegani, Maria Isabella, Carlone, Sebastiano, Morbelli, Silvia, Ravera, Silvia, Sambuceti, Gianmario, Marini, Cecilia
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2020
Témata:
Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163080/
https://ncbi.nlm.nih.gov/pubmed/32302773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100752
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