A time-dependent role for the transcription factor CREB in neuronal allocation to an engram underlying a fear memory revealed using a novel in vivo optogenetic tool to modulate CREB function

The internal representation of an experience is thought to be encoded by long-lasting physical changes to the brain (“engrams”) . Previously, we and others showed within the lateral amygdala (LA), a region critical for auditory conditioned fear, eligible neurons compete against one other for allocat...

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Bibliografiset tiedot
Julkaisussa:Neuropsychopharmacology
Päätekijät: Park, Albert, Jacob, Alexander D., Walters, Brandon J., Park, Sungmo, Rashid, Asim J., Jung, Jung Hoon, Lau, Jocelyn, Woolley, G. Andrew, Frankland, Paul W., Josselyn, Sheena A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer International Publishing 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162924/
https://ncbi.nlm.nih.gov/pubmed/31837649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0588-0
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