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Development of a tunable method to generate various three-dimensional microstructures by replenishing macromolecules such as extracellular matrix components and polysaccharides

Multicellular spheroids (spheroids) are expected to be a promising approach to mimic in vivo organ functions and cell microenvironments. However, conventional spheroids do not fully consider the existence of extracellular matrices (ECMs). In this study, we developed a tunable method for replenishing...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tao, Fumiya, Sayo, Kanae, Sugimoto, Kazuyuki, Aoki, Shigehisa, Kojima, Nobuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162899/
https://ncbi.nlm.nih.gov/pubmed/32300241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63621-4
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