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Repurposing a platelet aggregation inhibitor ticagrelor as an antimicrobial against Clostridioides difficile

Drug resistance in Clostridioides difficile becomes a public health concern worldwide, especially as the hypervirulent strains show decreased susceptibility to the first-line antibiotics for C. difficile treatment. Therefore, the simultaneous discovery and development of new compounds to fight this...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Phanchana, Matthew, Phetruen, Tanaporn, Harnvoravongchai, Phurt, Raksat, Ponlawoot, Ounjai, Puey, Chankhamhaengdecha, Surang, Janvilisri, Tavan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162883/
https://ncbi.nlm.nih.gov/pubmed/32300130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63199-x
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