Characterization of Schu S4 aro mutants as live attenuated tularemia vaccine candidates

There is a need for development of an effective vaccine against Francisella tularensis, as this potential bioweapon has a high mortality rate and low infectious dose when delivered via the aerosol route. Moreover, this Tier 1 agent has a history of weaponization. We engineered targeted mutations in...

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Publicado en:Virulence
Autores principales: Cunningham, Aimee L., Mann, Barbara J., Qin, Aiping, Santiago, Araceli E., Grassel, Christen, Lipsky, Michael, Vogel, Stefanie N., Barry, Eileen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161688/
https://ncbi.nlm.nih.gov/pubmed/32241221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2020.1746557
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