Molecularly defined extraintestinal pathogenic Escherichia coli status predicts virulence in a murine sepsis model better than does virotype, individual virulence genes, or clonal subset among E. coli ST131 isolates

Background: Escherichia coli ST131, mainly its H30 clade, is the leading cause of extraintestinal E. coli infections but its correlates of virulence are undefined. Materials and methods: We tested in a murine sepsis model 84 ST131 isolates that differed by country of origin (Spain vs. USA), clonal s...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Virulence
Päätekijät: Merino, Irene, Porter, Stephen B., Johnston, Brian, Clabots, Connie, Thuras, Paul, Ruiz-Garbajosa, Patricia, Cantón, Rafael, Johnson, James R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2020
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161687/
https://ncbi.nlm.nih.gov/pubmed/32264739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2020.1747799
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