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The Diversity Outbred Mouse Population Is an Improved Animal Model of Vaccination against Tuberculosis That Reflects Heterogeneity of Protection

Many studies of Mycobacterium tuberculosis infection and immunity have used mouse models. However, outcomes of vaccination and challenge with M. tuberculosis in inbred mouse strains do not reflect the full range of outcomes seen in people. Previous studies indicated that the novel Diversity Outbred...

詳細記述

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書誌詳細
出版年:mSphere
主要な著者: Kurtz, Sherry L., Rossi, Amy P., Beamer, Gillian L., Gatti, Dan M., Kramnik, Igor, Elkins, Karen L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160682/
https://ncbi.nlm.nih.gov/pubmed/32295871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00097-20
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