Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss

In the inner ear, cyclic guanosine monophosphate (cGMP) signaling has been described as facilitating otoprotection, which was previously observed through elevated cGMP levels achieved by phosphodiesterase 5 inhibition. However, to date, the upstream guanylyl cyclase (GC) subtype eliciting cGMP produ...

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Publicado en:Front Aging Neurosci
Autores principales: Marchetta, Philine, Möhrle, Dorit, Eckert, Philipp, Reimann, Katrin, Wolter, Steffen, Tolone, Arianna, Lang, Isabelle, Wolters, Markus, Feil, Robert, Engel, Jutta, Paquet-Durand, François, Kuhn, Michaela, Knipper, Marlies, Rüttiger, Lukas
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160671/
https://ncbi.nlm.nih.gov/pubmed/32327991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00083
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