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Impact of deoxycholate on Clostridioides difficile growth, toxin production, and sporulation

PURPOSE: Bile acids play an important role in Clostridioides difficile life cycle. Deoxycholate (DCA), one of the most abundant secondary bile acids, is known to inhibit vegetative growth and toxin production. However, limited data are available on the role of DCA on C. difficile sporulation. Here,...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Usui, Yukino, Ayibieke, Alafate, Kamiichi, Yuko, Okugawa, Shu, Moriya, Kyoji, Tohda, Shuji, Saito, Ryoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160582/
https://ncbi.nlm.nih.gov/pubmed/32322715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e03717
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