C-KIT Expression Distinguishes Fetal from Postnatal Skeletal Progenitors

Hematopoietic stem cells (HSCs) and skeletal stem cells (SSCs) cohabit in the bone marrow. KITL (C-KIT ligand) from LEPR(+) adult bone marrow stromal cells is pivotal for HSC maintenance. In contrast, it remains unclear whether KITL/C-KIT signaling also regulates SSCs. Here, we lineage traced C-KIT(...

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Udgivet i:Stem Cell Reports
Main Authors: He, Di Demi, Tang, Xinyu Thomas, Dong, Wenjie, Cui, Guizhong, Peng, Guangdun, Yin, Xiujuan, Chen, Yujie, Jing, Naihe, Zhou, Bo O.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160391/
https://ncbi.nlm.nih.gov/pubmed/32220331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.03.001
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