Memory of Divisional History Directs the Continuous Process of Primitive Hematopoietic Lineage Commitment

Hematopoietic stem cells (HSCs) exist in a dormant state and progressively lose regenerative potency as they undergo successive divisions. Why this functional decline occurs and how this information is encoded is unclear. To better understand how this information is stored, we performed RNA sequenci...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Bernitz, Jeffrey M., Rapp, Katrina, Daniel, Michael G., Shcherbinin, Dmitrii, Yuan, Ye, Gomes, Andreia, Waghray, Avinash, Brosh, Ran, Lachmann, Alexander, Ma'ayan, Avi, Papatsenko, Dmitri, Moore, Kateri A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160360/
https://ncbi.nlm.nih.gov/pubmed/32243840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.03.005
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