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CD4(+) T Cells in the Blood of MS Patients Respond to Predicted Epitopes From B cell Receptors Found in Spinal Fluid

B cells are important pathogenic players in multiple sclerosis (MS), but their exact role is not known. We have previously demonstrated that B cells from cerebrospinal fluid (CSF) of MS patients can activate T cells that specifically recognize antigenic determinants (idiotopes) from their B cell rec...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Høglund, Rune A., Bremel, Robert D., Homan, E. Jane, Torsetnes, Silje Bøen, Lossius, Andreas, Holmøy, Trygve
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160327/
https://ncbi.nlm.nih.gov/pubmed/32328067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00598
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