Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II

Human embryonic stem cell-derived retinal pigment epithelial (hESC-RPE) cells could serve as a replacement therapy in advanced stages of age-related macular degeneration. However, allogenic hESC-RPE transplants trigger immune rejection, supporting a strategy to evade their immune recognition. We est...

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Udgivet i:Stem Cell Reports
Main Authors: Petrus-Reurer, Sandra, Winblad, Nerges, Kumar, Pankaj, Gorchs, Laia, Chrobok, Michael, Wagner, Arnika Kathleen, Bartuma, Hammurabi, Lardner, Emma, Aronsson, Monica, Plaza Reyes, Álvaro, André, Helder, Alici, Evren, Kaipe, Helen, Kvanta, Anders, Lanner, Fredrik
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160308/
https://ncbi.nlm.nih.gov/pubmed/32197113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.02.006
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