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Autonomous synthesis and assembly of a ribosomal subunit on a chip

Ribosome biogenesis is an efficient and complex assembly process that has not been reconstructed outside a living cell so far, yet is the most critical step for establishing a self-replicating artificial cell. We recreated the biogenesis of Escherichia coli’s small ribosomal subunit by synthesizing...

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Veröffentlicht in:Sci Adv
Hauptverfasser: Levy, Michael, Falkovich, Reuven, Daube, Shirley S., Bar-Ziv, Roy H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159907/
https://ncbi.nlm.nih.gov/pubmed/32494616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz6020
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