Super-resolution imaging reveals the nanoscale organization of metabotropic glutamate receptors at presynaptic active zones

G protein–coupled receptors (GPCRs) play a fundamental role in the modulation of synaptic transmission. A pivotal example is provided by the metabotropic glutamate receptor type 4 (mGluR4), which inhibits glutamate release at presynaptic active zones (AZs). However, how GPCRs are organized within AZ...

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Pubblicato in:Sci Adv
Autori principali: Siddig, Sana, Aufmkolk, Sarah, Doose, Sören, Jobin, Marie-Lise, Werner, Christian, Sauer, Markus, Calebiro, Davide
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159906/
https://ncbi.nlm.nih.gov/pubmed/32494600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay7193
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