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Isoelectric point region pI≈7.4 as a treasure island of abnormal proteoforms in blood

Theoretical distribution of isoelectric points (pI values) of human blood proteins exhibits multi-modality with a deep minimum in the range between pI 7.30 and 7.50. Considering that the pH of human blood is 7.4±0.1, normal forms of human proteins tend to eschew this specific pI region, thus avoidin...

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Detalhes bibliográficos
Publicado no:Discoveries (Craiova)
Main Authors: Pirmoradian, Mohammad, Aarsland, Dag, Zubarev, Roman A.
Formato: Artigo
Idioma:Inglês
Publicado em: Applied Systems srl 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159840/
https://ncbi.nlm.nih.gov/pubmed/32309586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15190/d.2016.14
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