APOB‐associated cholesterol deficiency in Holstein cattle is not a simple recessive disease

In 2015, cholesterol deficiency (CD) was reported for the first time as a new recessive defect in Holstein cattle. After GWAS mapping and identification of a disease‐associated haplotype, a causative loss‐of‐function variant in APOB was identified. CD‐clinically affected APOB homozygotes showed poor...

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Sparad:
Bibliografiska uppgifter
I publikationen:Anim Genet
Huvudupphovsmän: Häfliger, Irene Monika, Hofstetter, Sonja, Mock, Thomas, Stettler, Manuela Hanna, Meylan, Mireille, Mehinagic, Kemal, Stokar‐Regenscheit, Nadine, Drögemüller, Cord
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Short Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159454/
https://ncbi.nlm.nih.gov/pubmed/31215050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/age.12801
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