Disruption of genes associated with Charcot-Marie-Tooth type 2 lead to common behavioural, cellular and molecular defects in Caenorhabditis elegans

Charcot-Marie-Tooth (CMT) disease is an inherited peripheral motor and sensory neuropathy. The disease is divided into demyelinating (CMT1) and axonal (CMT2) neuropathies, and although we have gained molecular information into the details of CMT1 pathology, much less is known about CMT2. Due to its...

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Publicat a:PLoS One
Autors principals: Soh, Ming S., Cheng, Xinran, Vijayaraghavan, Tarika, Vernon, Arwen, Liu, Jie, Neumann, Brent
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159224/
https://ncbi.nlm.nih.gov/pubmed/32294113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231600
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