Detection of microbial cell-free DNA in maternal and umbilical cord plasma in patients with chorioamnionitis using next generation sequencing

BACKGROUND: Chorioamnionitis has been linked to spontaneous preterm labor and complications such as neonatal sepsis. We hypothesized that microbial cell-free (cf) DNA would be detectable in maternal plasma in patients with chorioamnionitis and could be the basis for a non-invasive method to detect f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Witt, Russell G., Blair, Lily, Frascoli, Michela, Rosen, Michael J., Nguyen, Quoc-Hung, Bercovici, Sivan, Zompi, Simona, Romero, Roberto, Mackenzie, Tippi C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159194/
https://ncbi.nlm.nih.gov/pubmed/32294121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231239
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