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Clustering of continuous and binary outcomes at the general practice level in individually randomised studies in primary care - a review of 10 years of primary care trials

BACKGROUND: In randomised controlled trials, the assumption of independence of individual observations is fundamental to the design, analysis and interpretation of studies. However, in individually randomised trials in primary care, this assumption may be violated because patients are naturally clus...

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Foilsithe in:BMC Med Res Methodol
Main Authors: Stuart, Beth, Becque, Taeko, Moore, Michael, Little, Paul
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158044/
https://ncbi.nlm.nih.gov/pubmed/32293280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-00971-7
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