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Clustering of continuous and binary outcomes at the general practice level in individually randomised studies in primary care - a review of 10 years of primary care trials

BACKGROUND: In randomised controlled trials, the assumption of independence of individual observations is fundamental to the design, analysis and interpretation of studies. However, in individually randomised trials in primary care, this assumption may be violated because patients are naturally clus...

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Pubblicato in:BMC Med Res Methodol
Autori principali: Stuart, Beth, Becque, Taeko, Moore, Michael, Little, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158044/
https://ncbi.nlm.nih.gov/pubmed/32293280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-00971-7
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