Global Trends in Proteome Remodeling of the Outer Membrane Modulate Antimicrobial Permeability in Klebsiella pneumoniae

In Gram-negative bacteria, the permeability of the outer membrane governs rates of antibiotic uptake and thus the efficacy of antimicrobial treatment. Hydrophilic drugs like β-lactam antibiotics depend on diffusion through pore-forming outer membrane proteins to reach their intracellular targets. In...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Rocker, Andrea, Lacey, Jake A., Belousoff, Matthew J., Wilksch, Jonathan J., Strugnell, Richard A., Davies, Mark R., Lithgow, Trevor
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157821/
https://ncbi.nlm.nih.gov/pubmed/32291303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00603-20
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