Visualizing Association of the Retroviral Gag Protein with Unspliced Viral RNA in the Nucleus

Packaging of genomic RNA (gRNA) by retroviruses is essential for infectivity, yet the subcellular site of the initial interaction between the Gag polyprotein and gRNA remains poorly defined. Because retroviral particles are released from the plasma membrane, it was previously thought that Gag protei...

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Publicat a:mBio
Autors principals: Maldonado, Rebecca J. Kaddis, Rice, Breanna, Chen, Eunice C., Tuffy, Kevin M., Chiari, Estelle F., Fahrbach, Kelly M., Hope, Thomas J., Parent, Leslie J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157774/
https://ncbi.nlm.nih.gov/pubmed/32265329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00524-20
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