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Histidine-Triad Hydrolases Provide Resistance to Peptide-Nucleotide Antibiotics
The Escherichia coli microcin C (McC) and related compounds are potent Trojan horse peptide-nucleotide antibiotics. The peptide part facilitates transport into sensitive cells. Inside the cell, the peptide part is degraded by nonspecific peptidases releasing an aspartamide-adenylate containing a pho...
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| 出版年: | mBio |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7157772/ https://ncbi.nlm.nih.gov/pubmed/32265328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00497-20 |
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