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Protection and Safety Evaluation of Live Constructions Derived from the Pgm(−) and pPCP1(−) Yersinia pestis Strain
Based on a live attenuated Yersinia pestis KIM10(pCD1Ap) strain (Pgm(−), pPCP1(−)), we attempted to engineer its lipid A species to achieve improvement of immunogenicity and safety. A mutant strain designated as YPS19(pCD1Ap), mainly synthesizing the hexa-acylated lipid A, and another mutant strain...
Uloženo v:
| Vydáno v: | Vaccines (Basel) |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7157699/ https://ncbi.nlm.nih.gov/pubmed/32098032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010095 |
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