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Specific Substitutions in Region V2 of gp120 env confer SHIV Neutralisation Resistance

A tier 2 SHIV-MK38 strain was obtained after two in vivo passages of tier 1 SHIV-MK1. SHIV-MK38#818, cloned from the MK38 strain, was neutralisation-resistant, like the parental MK38 strain, to SHIV-infected monkey plasma (MP), HIV-1-infected human pooled plasma (HPP), and KD247 monoclonal antibody...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pathogens
Prif Awduron: Pisil, Yalcin, Yazici, Zafer, Shida, Hisatoshi, Matsushita, Shuzo, Miura, Tomoyuki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157653/
https://ncbi.nlm.nih.gov/pubmed/32138199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens9030181
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