Loading...

Antigen-Based Nano-Immunotherapy Controls Parasite Persistence, Inflammatory and Oxidative Stress, and Cardiac Fibrosis, the Hallmarks of Chronic Chagas Cardiomyopathy, in A Mouse Model of Trypanosoma cruzi Infection

Chagas cardiomyopathy is caused by Trypanosoma cruzi (Tc). We identified two candidate antigens (TcG2 and TcG4) that elicit antibodies and T cell responses in naturally infected diverse hosts. In this study, we cloned TcG2 and TcG4 in a nanovector and evaluated whether nano-immunotherapy (referred a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Vaccines (Basel)
Main Authors: Lokugamage, Nandadeva, Choudhuri, Subhadip, Davies, Carolina, Chowdhury, Imran Hussain, Garg, Nisha Jain
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157635/
https://ncbi.nlm.nih.gov/pubmed/32098116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010096
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!