Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci

Streptococcus pneumoniae (or pneumococcus) is a highly prevalent human pathogen. Toll-like receptors (TLRs) function as immune sensors that can trigger host defenses against this bacterium. Defects in TLR-activated signaling pathways, including deficiency in the adaptor protein myeloid differentiati...

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Veröffentlicht in:mBio
Hauptverfasser: Famà, Agata, Midiri, Angelina, Mancuso, Giuseppe, Biondo, Carmelo, Lentini, Germana, Galbo, Roberta, Giardina, Maria Miriam, De Gaetano, Giuseppe Valerio, Romeo, Letizia, Teti, Giuseppe, Beninati, Concetta
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157524/
https://ncbi.nlm.nih.gov/pubmed/32209688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00415-20
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